Chou, Tzung-Han

Professor

• TitleProfessor
• Education​Ph.D., Chemical Engineering, National Tsing Hua University
• E-mailchouth@yuntech.edu.tw
• SpecialtyInterfacial Science, Biotechnology, Drug Delivery, Cosmetics
• OfficeEC316
• Tel+886-5-5342601(ext 4625)
• LaboratoryInterface Science and Biotechnology Lab(EC418)
• Tel4688
• CoursesProgram Control, Intellectual Property Rights and Engineering Ethics
• BookURL link

The main research areas:

• Pharmaceutical dosage form design and preparation
• Biomedical materials
• thermodynamics
• interface science
• Nano Biotechnology Cosmetics
• Preparation of cosmetic carrier and efficacy assessment

Publications and patents in the past three years:

1. Tzung-Han Chou (周宗翰)*, Chien-Wen Chen(陳建文), Chia-Hua Liang, Li-Hsien Yeh, Shizhi Qian, “Simple synthesis, self-assembly, and cytotoxicity of novel dimeric cholesterol derivatives.” Colloids and Surfaces B: Biointerfaces, 116, 153-159 (April 2014). (SCI) [2013 Impact factor: 4.287], [Biophysics, 14/74]
2. Chia-Hua Liang, Li-Hsien Yeh, Pei-Wen Liao, Tzung-Han Chou*, “Characterization and in vitro biocompatibility of catanionic assemblies formed with oppositely charged dicetyl amphiphiles.” Colloids and Surfaces B: Biointerfaces 126, 10-17. (February 2015). (SCI) [2013 Impact factor: 4.287], [Biophysics, 14/74]
3. Yu-Shen Cheng, Kuan-Yu Chen, and Tzung-Han Chou. “Concurrent calcium peroxide pretreatment and wet storage of water hyacinth for fermentable sugar production.” Bioresource technology 176, 267-272 (January 2015). (SCI) [2013 Impact factor: 5.039], [Biotechnology & Applied microbiology, 17/165]
4. Zachary Milne, Li-Hsien Yeh, Tzung-Han Chou, Shizhi Qian, “Tunable donnan potential and electrokinetic flow in a biomimetic gated nanochannel with pH-regulated polyelectrolyte brushes.” The Journal of Physical Chemistry C 118, 19806-19813 (August 2014). (SCI) [2013 Impact factor: 4.835], [Materials science, Multidisciplinary, 29/251]
5. Tzung-Han Chou*, Chia-Hua Liang, Yu-Chieh Lee, Li-Hsien Yeh, “Effects of lipid composition on physicochemical characteristics and cytotoxicity of vesicles composed of cationic and anionic dialkyl lipids.” Physical Chemistry Chemical Physics 16, 1545-1553 (January 2014). (SCI) [2013 Impact factor: 4.198], [Physics, Atomic, Molecular & Chemical, 5/33]
6. Laura Benson, Li-Hsien Yeh, Tzung-Han Chou, Shizhi Qian, “Field effect regulation of Donnan potential and electrokinetic flow in a functionalized soft nanochannel.” Soft Matter, 9, 9767-9773 (November 2013). (SCI) [2013 Impact factor: 4.151], [Materials science, Multidisciplinary, 33/251]
7. Chia-Hua Liang, Wen-Yueh Ho, Li-Hsien Yeh, Yu-Shen Cheng, Tzung-Han Chou*, “Effects of 1-hexadecyl-3-methylimidazolium ionic liquids on the physicochemical characteristics and cytotoxicity of phosphatidylcholine vesicles.” Colloids and Surfaces A: Physicochemical and Engineering Aspects, 436, 1083-1091 (September 2013). (SCI) [2013 Impact factor: 2.354], [Chemistry, Physical, 59/136]
8. Rong-Jyh Lin, Chuan-Min Yen, Tzung-Han Chou, Feng-Yu Chiang, Guey-Horng Wang, Ya-Ping Tseng, Lin Wang, Ting-Wei Huang, Hui-Chuan Wang, Leong-Perng Chan, Hsiou-Yu Ding, Chia-Hua Liang, “Antioxidant, anti-adipocyte differentiation, antitumor activity and anthelmintic activities against Anisakis simplex and Hymenolepis nana of yakuchinone A from Alpinia oxyphylla.” BMC complementary and alternative medicine, 13(1), 237-250 (September, 2013). (SCI) [2013 Impact factor: 1.877], [Integrative & Complementary Medicine, 8/22]
9. Chia-Hua Liang, Leong-Perng Chan, Tzung-Han Chou, Feng-Yu Chiang,Chuan-Min Yen, Pin-Ju Chen, Hsiou-Yu Ding, Rong-Jyh Lin, “Brazilein from Caesalpinia sappan L. antioxidant inhibits adipocyte differentiation and induces apoptosis through caspase-3 activity and anthelmintic activities against Hymenolepis nana and Anisakis simplex.” Evidence-Based Complementary and Alternative Medicine, 2013, 1-14 (February, 2013). (SCI) [2013 Impact factor: 2.175], [Integrative & Complementary Medicine, 6/22]
10. Leong-Perng Chan, Tzung-Han Chou, Guey-Horng Wang,Ya-Ping Tseng, Pin-JuChen, Da-Long Cheng, Chia-Hua Liang, “Ugonin K induces cell cycle arrest and apoptosis through reactive oxygen species/apoptosis signal pathway in human skin cancer cells.” Advanced Materials Research, 690, 1422-1425 (May, 2013). (EI)
11. Chia-Hua Liang, Tzung-Han Chou, Ya-Ping Tseng, Hsiou-Yu Ding, “trans-Caffeic acid stearyl ester from Paeonia suffruticosa inhibits melanin synthesis by cAMP-mediating down-regulation of α-melanocyte-stimulating hormone-stimulated melanogenesis signaling pathway in B16 cells.” Biological and Pharmaceutical Bulletin, 35, 2198-2203 (September, 2012). (SCI) [2013 Impact factor: 1.778] [Pharmacology & Pharmacy, 161/256]
12. Chia-Hua Liang, Leong-Perng Chan, Hsiou-Yu Ding, Edmund Cheung So, Rong-Jyh Lin, Hui-Min Wang, Ying-Ging Chen, Tzung-Han Chou*, “Free radical scavenging activity of 4-(3,4-dihydroxybenzoyloxymethyl)phenyl-o-β-d-glucopyranoside from Origanum vulgare and its protection against oxidative damage.” Journal of Agricultural and Food Chemistry, 60, 7690-7696 (July, 2012). (SCI) [2013 Impact factor: 3.107], [Agriculture, Multidisciplinary, 2/56]
13. Chia-Hua Liang, Guey-Horng Wang, Tzung-Han Chou, Shih-Hao Wang, Rong-Jyh Lin, Leong-Perng Chan, Edmund Cheung So, Jyh-Horng Sheu, “5-epi-sinuleptolide induces cell cycle arrest and apoptosis through tumor necrosis factor/mitochondria-mediated caspase signaling pathway in human skin cancer cells.” Biochimica et Biophysica Acta (BBA) – General Subjects, 1820, 1149-1157 (July, 2012). (SCI) [2013 Impact factor: 3.829], [Biophyics, 19/74]
14. Leong-Perng Chan, Tzung-Han Chou, Hsiou-Yu Ding, Pin-Ru Chen, Feng-Yu Chiang, Po-Lin Kuo, Chia-Hua Liang, “Apigenin induces apoptosis via tumor necrosis factor receptor- and Bcl-2-mediated pathway and enhances susceptibility of head and neck squamous cell carcinoma to 5-fluorouracil and cisplatin.” Biochimica et Biophysica Acta (BBA) – General Subjects, 1820, 1081-1091 (July, 2012). (SCI) [2013 Impact factor: 3.829], [Biophyics, 19/74]
15. Chien-Hsiang Chang, Chia-Hua Liang, Yu-Ying Hsieh, Tzung-Han Chou*, “Molecular packing and lateral interactions of distearoylphosphatidylcholine with dihexadecyldimethylammonium bromide in langmuir monolayers and vesicles.” Journal of Physical Chemistry B, 116, 2455-2463 (February, 2012) (SCI) [2013 Impact factor: 3.337], [Chemistry, Physical, 39/136]
16. Tzung-Han Chou*, “Current application of lipid- and surfactant-based vesicles for cosmeceuticals: a review” Current Pharmaceutical Biotechnology, in press, (February, 2015) (SCI) [2013 Impact factor: 2.511], [Pharmacology & Pharmacy, 112/256]
17. Tzung-Han Chou*, Chien-Wen Chen “Synthesis, self-assembly, and in vitro biocompatibility of a novel steroidal oxime.” Current Pharmaceutical Biotechnology, in press, (September, 2014) (SCI) [2013 Impact factor: 2.511], [Pharmacology & Pharmacy, 112/256]

Book:

1. 周宗翰、張乃方、呂祖尚、陳玉芬、嚴嘉蕙、楊濟華，”界面化學(二版)”，第1章表面張力與界面張力，p1.1-1.13，2013，02，華格那企業有限公司，ISBN 978-986-5929-88-6。
2. 周宗翰、梁家華， “奈米液胞化妝品的開發與應用”，化工技術，Vol.225，p122-130，(December, 2011)，ISSN 1814-9154。

Patent:

1. 丁秀玉、梁家華、周宗翰 ， “用於防止黑色素沉澱之沙苑子萃取物”， 中華民國，發明專利，第I477292，民國103(2015)年03月21日。
2. 丁秀玉、梁家華、周宗翰， “用於防止黑色素沉澱之防風草萃取物”， 中華民國，發明專利，第I474828，民國103(2015)年03月01日。
3. 周宗翰、梁家華、蕭靖樺， “用於皮膚美白之奈米聚集體及其製造方法”，中華民國，發明專利，第I457140，民國103(2014)年10月21日。
4. 周宗翰、梁家華、洪偉章， “含有蘆薈羥基蔥?衍生物之微脂粒遞送系統及其製造方法”， 中華民國，發明專利，第I439294，民國103(2014)年6月1日。
5. 梁家華、周宗翰、丁秀玉 、洪偉章 、陳品儒， “利用吸光值變化定量評估抑制黑色素生成效果之方法” 中華民國，發明專利，第I439691，民國103(2014)年6月1日。
6. 丁秀玉、梁家華、周宗翰， “牡丹皮萃取物及其製造方法暨其抗氧化之應用”， 中華民國，發明專利，第I433690，民國103(2014)年04月11日。
7. 丁秀玉、梁家華、周宗翰， “牡丹皮萃取物及其製造方法暨其皮膚美白之應用”， 中華民國，發明專利，第I417127，民國102(2013)年12月01日。
8. 梁家華、丁秀玉、周宗翰，“來自牛至(Origanum vulgare) 之新化合物及其用途”，中華民國發明專利，第I386232，民國102(2013)年02月21日。
9. 梁家華、周宗翰、陳亭宇、曾雅萍、易采旋、陳品儒、程達隆， “動物固定裝置”，中華民國新型專利，M 420171，民國101(2012)年01月11日。

Projects executed by former host within three years:

Other awards: